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Pomalidomide, sold under the brand names Pomalyst and Imnovid, [7] [8] is an anti-cancer medication used for the treatment of multiple myeloma and AIDS-related Kaposi sarcoma. [ 7 ] Pomalidomide was approved for medical use in the United States in February 2013, [ 10 ] and in the European Union in August 2013. [ 8 ]
The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.
$20.99 at Amazon. Orange Vitamin D3. Rated at 4.7 stars by over 6,000 happy customers on Amazon, this daily vitamin is a tried-and-true product that's affordable and even offers a refreshing ...
Mary Lou Spiess (1931–1992) – American designer of disabled fashion, paralyzed as a result of polio. [37] Darryl Stingley (1951–2007) – American football player, paralyzed in a 1978 exhibition game. [38] Sam Sullivan (born 1959) – Canadian politician, mayor of Vancouver from 2005 to 2008. Paralyzed in a skiing accident at age 19. [39]
Jessie Owen was traveling with her family twelve years ago when, while going through a mountain pass, a tree fell on their car. “In that moment, my parents passed away, my siblings were severely ...
The U.S. Preventive Services Task Force released a draft recommendation advising against using vitamin D to prevent falls and fractures in people over 60. Pharmacist Katy Dubinsky weighs in.
Lenalidomide is used to treat multiple myeloma. [11] It is a more potent molecular analog of thalidomide, which inhibits tumor angiogenesis, tumor-secreted cytokines, and tumor proliferation through induction of apoptosis.
Take it easy with alcohol. Research finds that so-called "heavy" drinkers are more likely to develop dementia than "moderate" ones. But there's good news: Even dropping your drinking levels from ...