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Cardiotoxicity may be caused by chemotherapy (a usual example is the class of anthracyclines) [3] [4] treatment and/or radiotherapy; [5] complications from anorexia nervosa; adverse effects of heavy metals intake; [6] the long-term abuse of or ingestion at high doses of certain strong stimulants such as cocaine; [7] or an incorrectly ...
Atrioventricular reentrant tachycardia (AVRT), or atrioventricular reciprocating tachycardia, is a type of heart arrhythmia with an abnormally fast rhythm (tachychardia); it is classified as a type of supraventricular tachycardia (SVT).
Two distinct drug classes in which cardiotoxicity can occur are in anti-cancer and antiarrhythmic drugs. Anti-cancer drug classes that cause cardiotoxicity include anthracyclines, monoclonal antibodies, and antimetabolites. This form generally manifests as a progressive form of heart failure, but can also manifest as an harmful arrhythmia. [2]
There are no formal diagnostic criteria for TIC. Thus, TIC is typically diagnosed when (1) tests have excluded other causes of cardiomyopathy and (2) there is improvement in myocardial function after treatment of the tachycardia or arrhythmia. [1] [5] [6] Treatment of TIC can involve treating the heart failure as well as the tachycardia or ...
Several groups of drugs slow conduction through the heart, without actually preventing an arrhythmia. These drugs can be used to "rate control" a fast rhythm and make it physically tolerable for the patient. [citation needed] Some arrhythmias promote blood clotting within the heart and increase the risk of embolus and stroke.
Numerous studies have been conducted on the use of ICDs for the secondary prevention of SCD. These studies have shown improved survival with ICDs compared to the use of anti-arrhythmic drugs. [75] ICD therapy is associated with a 50% relative risk reduction in death caused by an arrhythmia and a 25% relative risk reduction in all-cause ...
However, if the abnormal heart rhythm continues, it can degenerate into a more dangerous arrhythmia known as ventricular fibrillation causing a cardiac arrest and, if untreated, sudden death. [10] There are typically very few abnormal signs on clinical examination in persons with CPVT.
PJRT can cause chronic tachycardia that, untreated, leads to cardiomyopathy. The cause is an accessory pathway in the heart which conducts from the ventricles back to the atria . Unlike the accessory pathway in a more common cause of AVRT, Wolff–Parkinson–White syndrome , the accessory pathway in PJRT conducts slowly.