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Congenital cytomegalovirus (cCMV) is cytomegalovirus (CMV) infection in a newborn baby. [1] Most have no symptoms. [1] Some affected babies are small. [1] Other signs and symptoms include a rash, jaundice, hepatomegaly, retinitis, and seizures. [1] [2] It may lead to loss of hearing or vision, developmental disability, or a small head. [1]
Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that can lead to blindness. [1] Caused by human cytomegalovirus , it occurs predominantly in people whose immune system has been compromised, including 15-40% of those with AIDS.
Cytomegalovirus (CMV) is the most common congenital viral infection, usually transmitted through the placenta during pregnancy. Most neonates with congenital CMV infection will not have any symptoms, but a minority of infected newborns will have symptomatic infection.
CMV placentitis. When physical examination of the newborn shows signs of a vertically transmitted infection, the examiner may test blood, urine, and spinal fluid for evidence of the infections listed above. Diagnosis can be confirmed by culture of one of the specific pathogens or by increased levels of IgM against the pathogen. [citation needed]
Cytomegalovirus (CMV) (from cyto-'cell' via Greek κύτος kútos - 'container' + μέγας mégas 'big, megalo-' + -virus via Latin vīrus 'poison') is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, [3] in the subfamily Betaherpesvirinae. Humans and other primates serve as natural hosts.
A new father with a degenerative eye disease was able to see his newborn son for the first time, thanks to a genetic therapy that helped restore partial sight to one of his eyes.
The CMV pp65 assay is widely used for monitoring CMV infection and its response to antiviral treatment in people who are under immunosuppressive therapy and have had renal transplantation surgery, as the antigenemia results are obtained about 5 days before the onset of symptomatic CMV disease.
Antibiotic ointment is typically applied to the newborn's eyes within 1 hour of birth as prevention for gonococcal ophthalmia. [3] This practice is recommended for all newborns and most hospitals in the United States are required by state law to apply eye drops or ointment soon after birth to prevent the disease. [4] [5]