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  2. Erythropoietin - Wikipedia

    en.wikipedia.org/wiki/Erythropoietin

    Erythropoietin (/ ɪ ˌ r ɪ θ r oʊ ˈ p ɔɪ. ɪ t ɪ n,-r ə-,-p ɔɪ ˈ ɛ t ɪ n,-ˈ iː t ɪ n /; [1] [2] [3] EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow.

  3. Erythropoiesis-stimulating agent - Wikipedia

    en.wikipedia.org/wiki/Erythropoiesis-stimulating...

    The 2020 Cochrane Anaesthesia Review Group review of erythropoietin (EPO) plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing non‐cardiac surgery [11] demonstrated that patients were much less likely to require red cell transfusion and in those transfused, the volumes were unchanged (mean ...

  4. Erythropoiesis - Wikipedia

    en.wikipedia.org/wiki/Erythropoiesis

    Erythropoiesis (from Greek 'erythro' meaning "red" and 'poiesis' "to make") is the process which produces red blood cells (erythrocytes), which is the development from erythropoietic stem cell to mature red blood cell. [1] It is stimulated by decreased O 2 in circulation, which is detected by the kidneys, which then secrete the hormone ...

  5. Polycythemia - Wikipedia

    en.wikipedia.org/wiki/Polycythemia

    Hypoxia: Poor oxygen delivery (hypoxia) in utero resulting in compensatory increased production of red blood cells (erythropoeisis). Hypoxia can be either acute or chronic. Acute hypoxia can occur as a result of perinatal complications. Chronic fetal hypoxia is associated with maternal risk factors such as hypertension, diabetes and smoking. [10]

  6. HIV isn't the death sentence it once was: How related deaths ...

    www.aol.com/hiv-isnt-death-sentence-once...

    Death rates fell among highly affected HIV subpopulations. Medical breakthroughs have reduced death rates for Americans with HIV, including groups that are disproportionately affected by the virus.

  7. HIF prolyl-hydroxylase inhibitor - Wikipedia

    en.wikipedia.org/wiki/HIF_prolyl-hydroxylase...

    Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a novel class of oral medications developed for the treatment of anemia in chronic kidney disease (CKD). These drugs work by inhibiting hypoxia-inducible factor-proline dioxygenase (HIF prolyl-hydroxylase), which are responsible for the degradation of hypoxia-inducible factor ...

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  9. Erythropoietin receptor - Wikipedia

    en.wikipedia.org/wiki/Erythropoietin_receptor

    The erythropoietin receptor (EpoR) is a protein that in humans is encoded by the EPOR gene. [5] EpoR is a 52 kDa peptide with a single carbohydrate chain resulting in an approximately 56–57 kDa protein found on the surface of EPO responding cells. It is a member of the cytokine receptor family. EpoR pre-exists as dimers.