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Transitional epithelium animation, highlighting the epithelial layer, then underlying connective tissue. Contrast the messy appearance of the epithelial surface to other epithelial tissues. Transitional epithelium is a type of stratified epithelium . [ 1 ]
System Tissue Epithelium Subtype; circulatory: blood vessels: Simple squamous: endothelium: digestive: ducts of submandibular glands: simple columnar - digestive ...
Transitional cell carcinoma is a type of cancer that arises from the transitional epithelium, a tissue lining the inner surface of these hollow organs. [1] It typically occurs in the urothelium of the urinary system ; in that case, it is also called urothelial carcinoma .
In biology, tissue is an assembly of similar cells and their extracellular matrix from the same embryonic origin that together carry out a specific function. [1] [2] Tissues occupy a biological organizational level between cells and a complete organ.
The epithelial–mesenchymal transition (EMT) is a process by which epithelial cells lose their cell polarity and cell–cell adhesion, and gain migratory and invasive properties to become mesenchymal stem cells; these are multipotent stromal cells that can differentiate into a variety of cell types.
The transitional epithelium may appear as a layer of column-shaped cells when relaxed, and of flatter cells when distended. Below the epithelium sits the lamina propria. The lamina propria is made up of loose connective tissue with many elastic fibers interspersed with blood vessels, veins and lymphatics.
Bladder tumors are classified by their appearance under the microscope, and by their cell type of origin. Over 90% of bladder tumors arise from the cells that form the bladder's inner lining, called urothelial cells or transitional cells; the tumor is then classified as urothelial cancer or transitional cell cancer.
- Cyst (may also be solid nest) of transitional type epithelium. - Eosinophilic luminal secretions. - Uniform nuclei with irregular borders and nuclear grooves (insert image). Micrograph of a cystic Walthard cell rest (lower right of image) within the connective tissue of a fallopian tube (tubal epithelium – upper left of image). H&E stain.