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Acephalgic migraine (also called migraine aura without headache, amigrainous migraine, isolated visual migraine, and optical migraine) is a neurological syndrome.It is a relatively uncommon variant of migraine in which the patient may experience some migraine symptoms such as aura, nausea, photophobia, and hemiparesis, but does not experience headache. [1]
Persistent aura without infarction (PAWOI) is a rare and seemingly benign [1] condition, first described in case reports in 1982 as "prolonged/persistent migraine aura status", [2] and in 2000 as "migraine aura status", [3] [4] that is not yet fully understood.
Scintillating scotoma is a common visual aura that was first described by 19th-century physician Hubert Airy (1838–1903). Originating from the brain, it may precede a migraine headache, but can also occur acephalgically (without headache), also known as visual migraine or migraine aura. [4]
Ubrogepant, sold under the brand name Ubrelvy, is a medication used for the acute (immediate) treatment of migraine with or without aura (a sensory phenomenon or visual disturbance) in adults. [4] [5] It is not indicated for the preventive treatment of migraine. [6] Ubrogepant is a small-molecule calcitonin gene-related peptide receptor antagonist.
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The difference is that oftentimes the aura is a warning sign that migraine pain is headed your way so it gives you an opportunity to initiate treatment and stop the migraine in its tracks ...
Rimegepant, sold under the brand name Nurtec ODT among others, is a medication used for the acute treatment of migraine with or without aura in adults and the prophylactic/ preventive treatment of episodic migraine in adults. [8] [10] It is taken by mouth to dissolve on or under the tongue. [8] It works by blocking CGRP receptors. [11]
The other was a control group and received sham stimulation. Patients in the treatment group reduced their number of migraine days per month by 5.5 from a baseline of 20.2 days per month. Patients in the control group reduced their number of migraine days per month by 3.9 from a baseline of 19.2 days per month.
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