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Sommer's Sector is region CA1 of the hippocampus, a part of the human brain. It is particularly vulnerable to hypoxic or ischemic damage and is one of the first brain regions to show gross changes in cerebral hypoxia. Sommer's sector is one of the vulnerable areas in global cerebral ischemia.
The application of memantine leads to in increase in place field plasticity in aged rat subjects. [84] Although memantine aids in the encoding process of spatial information in aged rat subjects, it does not help with the retrieval of this information later in time. Aged rats further show a high instability in their place cells in the CA1 region.
The reaction catalyzed by CA1 is the same as other carbonic anhydrase family proteins: + (in tissues - high CO 2 concentration) [9]. The CA1-catalyzed reaction has a relatively low reaction affinity (Km) of 4.0 mM for CO 2, [7] [10] turnover number (Kcat) of 2 × 10 5 s −1, and catalytic efficiency (Kcat/Km) of 5 × 10 7 M −1 s −1 comparing to other isozymes of the α-CA family of ...
Schaffer collaterals are the axons of the neurons in the CA3 regions of the hippocampus that form synapses in the CA1 regions. The hippocampus is a part of the feedback process that sends signals to stop cortisol production. Thus, a damaged hippocampus can cause memory loss and inability of cognitive function.
CA2 is a small region located between CA1 and CA3. It receives some input from layer II of the entorhinal cortex via the perforant path.Its pyramidal cells are more like those in CA3 than those in CA1.
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CA1 pyramidal cells make up a homogeneous population which together with relatives in subiculum comprise the primary output cells of the hippocampal formation. [2] Primary excitatory inputs are via glutamatergic CA3 Schaffer collaterals (both ipsi- and contralateral), which contact dendritic spines on the apical and basal dendrites in strata ...
CA1, CA-1, CA 1, or Ca.1 may refer to: Aircraft and other vehicles. Buhl CA-1 Airster, an American sports airplane; Caproni Ca.1 (1910), an experimental biplane of 1910;