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Neurotrophin-3, or NT-3, is a neurotrophic factor, in the NGF-family of neurotrophins. It is a protein growth factor that has activity on certain neurons of the peripheral and central nervous system ; it helps to support the survival and differentiation of existing neurons, and encourages the growth and differentiation of new neurons and synapses .
The p75 neurotrophin receptor (p75NTR) was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) [5] [6] before discovery that p75NTR bound other neurotrophins equally well as nerve growth factor. [7] [8] p75NTR is a neurotrophic factor receptor.
Neurotrophin-3 is a protein that in humans is encoded by the NTF3 gene. [ 5 ] [ 6 ] The protein encoded by this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins .
How much does the test cost? The Galleri test — which isn’t covered by insurance — doesn’t come cheap. At $949 a pop, it’s out of the price range of most people.
Neurotrophin mimetics are small molecules or peptide like molecules that can modulate the action of the neurotrophin receptor. One of the main causes of neurodegeneration involves changes in the expression of neurotrophins (NTs) and/or their receptors ( TrkA , TrkB , TrkC and p75NTR ).
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The Wechsler Adult Intelligence Scale (WAIS) is an Intelligence Quotient (IQ) test designed to measure intelligence and cognitive ability in adults and older adolescents. [1] For children between the ages of 6 and 16, Wechsler Intelligence Scale for Children (WISC) is commonly used.