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Norethisterone acetate (NETA), also known as norethindrone acetate and sold under the brand name Primolut-Nor among others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.
Side effects of norethisterone include menstrual irregularities, headaches, nausea, breast tenderness, mood changes, acne, increased hair growth. [ 16 ] [ 17 ] Norethisterone is a progestin, or a synthetic progestogen , and hence is an agonist of the progesterone receptor , the biological target of progestogens like progesterone .
[49] [50] However, the long term side effects common with oral contraceptives such as arterial disease are lower with levonorgestrel than in combination pills. [ medical citation needed ] Levonorgestrel as a contraceptive intrauterine device has been associated with a slightly higher risk of breast cancer than with non-use in select studies.
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Norethisterone enanthate (NETE), also known as norethindrone enanthate, is a form of hormonal birth control which is used to prevent pregnancy in women. [ 1 ] [ 2 ] [ 3 ] It is used both as a form of progestogen-only injectable birth control and in combined injectable birth control formulations.
Side effects can include nausea, headache, blood clots, breast pain, depression, and liver problems. [2] Use is not recommended during pregnancy, the initial three weeks after childbirth, and in those at high risk of blood clots. [2] [4] It, however, may be started immediately after a miscarriage or abortion. [4]
Relugolix acts as an GnRH antagonist, or an antagonist of the gonadotropin-releasing hormone receptor. [13] Estradiol is an estrogen, or an agonist of the estrogen receptors, whereas norethisterone acetate is a progestin (synthetic progestogen), or an agonist of the progesterone receptors. [14]
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