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Chiral drugs. Chemical compounds that come as mirror-image pairs are referred to by chemists as chiral or handed molecules. [ 1 ] Each twin is called an enantiomer. Drugs that exhibit handedness are referred to as chiral drugs. Chiral drugs that are equimolar (1:1) mixture of enantiomers are called racemic drugs and these are obviously devoid ...
The Scripps Research Institute. Doctoral advisor. E. J. Corey. Dale Lester Boger is an American medicinal and organic chemist and former chair of the Department of Chemistry [ 1 ] at The Scripps Research Institute in La Jolla, CA. Dale Boger was born on August 22, 1953, in Hutchinson, Kansas. He studied chemistry at the University of Kansas (B ...
Robert Burns Woodward ForMemRS HonFRSE (April 10, 1917 – July 8, 1979) was an American organic chemist.He is considered by many to be the preeminent synthetic organic chemist of the twentieth century, [3] having made many key contributions to the subject, especially in the synthesis of complex natural products and the determination of their molecular structure.
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs ...
Organoboron chemistry or organoborane chemistry studies organoboron compounds, also called organoboranes. These chemical compounds combine boron and carbon; typically, they are organic derivatives of borane (BH 3), as in the trialkyl boranes. [1][2] Organoboranes and -borates enable many chemical transformations in organic chemistry — most ...
Arne Jørgen Aasen (born 15 October 1939) is a Norwegian chemist and professor emeritus at the University of Oslo, School of Pharmacy. Aasen received his engineering degree in biochemistry and organic chemistry in 1964, and a doctorate (dr. ing.) [1] [2] in organic chemistry [3] in August 1966 from The Norwegian Institute of Technology ...
Chiral analysis refers to the quantification of component enantiomers of racemic drug substances or pharmaceutical compounds. Other synonyms commonly used include enantiomer analysis, enantiomeric analysis, and enantioselective analysis. Chiral analysis includes all analytical procedures focused on the characterization of the properties of ...
Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology ...