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  2. Breast development - Wikipedia

    en.wikipedia.org/wiki/Breast_development

    Estrogen, progesterone, and prolactin, as well as GH/IGF-1, produce their effects on breast development by modulating the local expression in breast tissue of an assortment of autocrine and paracrine growth factors, [25] [44] [62] [63] [64] including IGF-1, IGF-2, amphiregulin, [65] EGF, FGF, hepatocyte growth factor (HGF), [66] tumor necrosis factor α (TNF-α), tumor necrosis factor β (TNF ...

  3. Breast cancer - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer

    This is an accepted version of this page This is the latest accepted revision, reviewed on 16 February 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...

  4. 8 pictures to help you determine if a breast lump is cause ...

    www.aol.com/news/pictures-breast-cancer-lumps...

    For people with an average risk of breast cancer (meaning no family history or lifestyle factors that increase risk), doing a self-breast exam on a regular basis isn't necessary.

  5. High-dose estrogen therapy - Wikipedia

    en.wikipedia.org/wiki/High-dose_estrogen_therapy

    Natural pregnancy before the age of 20 has been associated with a 50% lifetime reduction in the risk of breast cancer. [56] Pseudopregnancy has been found to produce decreases in risk of mammary gland tumors in rodents similar to those of natural pregnancy, implicating high levels of estrogen and progesterone in this effect.

  6. Xenohormone - Wikipedia

    en.wikipedia.org/wiki/Xenohormone

    This disruption can lead to miscarriages, fertility problems, and irregular ovulation. Hormone imbalances in females caused by xenohormones caused health issues like thyroid cancer and polycystic ovary syndrome. There is also an increased risk on breast cancer or breast related disorders depending onto length of exposure to xenohormones.

  7. Estrogen deprivation therapy - Wikipedia

    en.wikipedia.org/wiki/Estrogen_deprivation_therapy

    Estrogen deprivation therapy, also known as endocrine therapy, is a form of hormone therapy that is used in the treatment of breast cancer.Modalities include antiestrogens or estrogen blockers such as selective estrogen receptor modulators (SERMs) like tamoxifen, selective estrogen receptor degraders like fulvestrant, and aromatase inhibitors like anastrozole and ovariectomy.

  8. Estrogen (medication) - Wikipedia

    en.wikipedia.org/wiki/Estrogen_(medication)

    The use of high-dose estrogen therapy in breast cancer has mostly been superseded by antiestrogen therapy due to the improved safety profile of the latter. [17] High-dose estrogen therapy was the standard of care for the palliative treatment of breast cancer in women up to the late 1970s or early 1980s. [18

  9. Triple-negative breast cancer - Wikipedia

    en.wikipedia.org/wiki/Triple-negative_breast_cancer

    Triple-negative breast cancer (TNBC) is any breast cancer that either lacks or shows low levels of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) overexpression and/or gene amplification (i.e. the tumor is negative on all three tests giving the name triple-negative). [1]