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[citation needed] Parasympathomimetic drugs (saliva stimulants) such as pilocarpine may improve xerostomia symptoms and other problems associated with salivary gland dysfunction, but the evidence for treatment of radiation-induced xerostomia is limited. [27] Both stimulants and substitutes relieve symptoms to some extent. [28]
The following are used in dentistry to treat xerostomia: [3] Parasympathomimetic drugs act on parasympathetic muscarinic receptors to induce an increased saliva flow. The M3 receptor has been identified as the principal target to increase salivary flow rates. [4] Pilocarpine is an example; the maximum dose of this drug is 30 mg/day ...
Pilocarpine stimulates the secretion of large amounts of saliva and sweat. [16] It is used to prevent or treat dry mouth, particularly in Sjögren syndrome, but also as a side effect of radiation therapy for head and neck cancer. [17] It may be used to help differentiate Adie syndrome from other causes of unequal pupil size. [18] [19]
Patients may watch for symptoms, such as shortness of breath, change in character or amount of mucus, and start self-treatment as discussed with a health care provider. This allows for treatment right away until a doctor can be seen. [5] The symptoms of acute exacerbations are treated using short-acting bronchodilators.
Garden cress seedlings Dermasterias imbricata. In nature, imidazole alkaloids are found both as secondary plant compounds and as byproducts of histidine metabolism in marine organisms.
Cevimeline is used in the treatment of xerostomia (dry mouth) [1 ... thereby alleviating dry mouth. ... Pilocarpine — a similar parasympathomimetic medication for ...
Different drugs can also be responsible for altering taste and resulting in dysgeusia. Due to the variety of causes of dysgeusia, there are many possible treatments that are effective in alleviating or terminating the symptoms. These include artificial saliva, pilocarpine, zinc supplementation, alterations in drug therapy, and alpha lipoic acid.
Pilocarpine is a drug that acts as a muscarinic receptor agonist that is used to treat glaucoma Cevimeline (AF102B) (Evoxac®) is a muscarinic agonist that is a Food and Drug Administration (FDA)- approved drug and used for the management of dry mouth in Sjögren's syndrome