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  2. Xerostomia - Wikipedia

    en.wikipedia.org/wiki/Xerostomia

    It was suggested that, barring any contraindications, a trial of the drug be offered in the above group (at a dose of five mg three times per day to minimize side effects). [6] Improvements can take up to twelve weeks. [6] However, pilocarpine is not always successful in improving xerostomia symptoms. [6]

  3. Pilocarpine - Wikipedia

    en.wikipedia.org/wiki/Pilocarpine

    Onset of effects with the drops is typically within an hour and lasts for up to a day. [1] By mouth it is used for dry mouth as a result of Sjögren syndrome or radiation therapy. [9] Common side effects of the eye drops include irritation of the eye, increased tearing, headache, and blurry vision. [1]

  4. Cevimeline - Wikipedia

    en.wikipedia.org/wiki/Cevimeline

    Known side effects include nausea, vomiting, diarrhea, excessive sweating, rash, headache, runny nose, cough, drowsiness, hot flashes, blurred vision, and difficulty sleeping. [3] Contraindications include asthma and angle closure glaucoma. [citation needed]

  5. Muscarinic agonist - Wikipedia

    en.wikipedia.org/wiki/Muscarinic_agonist

    Pilocarpine is a drug that acts as a muscarinic receptor agonist that is used to treat glaucoma Cevimeline (AF102B) (Evoxac®) is a muscarinic agonist that is a Food and Drug Administration (FDA)- approved drug and used for the management of dry mouth in Sjögren's syndrome

  6. Hypersalivation - Wikipedia

    en.wikipedia.org/wiki/Hypersalivation

    Mouthwash and tooth brushing may have drying effects. [4] In the palliative care setting, anticholinergics and similar drugs that would normally reduce the production of saliva causing a dry mouth could be considered for symptom management: scopolamine, atropine, propantheline, hyoscine, amitriptyline, glycopyrrolate. [9]

  7. Sialogogue - Wikipedia

    en.wikipedia.org/wiki/Sialogogue

    The following are used in dentistry to treat xerostomia: [3] Parasympathomimetic drugs act on parasympathetic muscarinic receptors to induce an increased saliva flow. The M3 receptor has been identified as the principal target to increase salivary flow rates. [4] Pilocarpine is an example; the maximum dose of this drug is 30 mg/day ...

  8. Cholinergic crisis - Wikipedia

    en.wikipedia.org/wiki/Cholinergic_crisis

    As a result of cholinergic crisis, the muscles stop responding to the high synaptic levels of acetylcholine, leading to flaccid paralysis, respiratory failure, and other signs and symptoms reminiscent of organophosphate poisoning. Other symptoms include increased sweating, salivation, bronchial secretions along with miosis (constricted pupils).

  9. Extrapyramidal symptoms - Wikipedia

    en.wikipedia.org/wiki/Extrapyramidal_symptoms

    Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.

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