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In August 2020, the U.S. Food and Drug Administration (FDA) became aware of nitrosamine impurities in certain samples of rifampin. [61] The FDA and manufacturers are investigating the origin of these impurities in rifampin, and the agency is developing testing methods for regulators and industry to detect the 1-methyl-4-nitrosopiperazine (MNP ...
The top horizontal line represents the maximum payload. It is limited structurally by maximum zero-fuel weight (MZFW) of the aircraft. Maximum payload is the difference between maximum zero-fuel weight and operational empty weight (OEW). Moving left-to-right along the line shows the constant maximum payload as the range increases.
The rifamycin group includes the classic rifamycin drugs as well as the rifamycin derivatives rifampicin (or rifampin), rifabutin, rifapentine, rifalazil and rifaximin. Rifamycin, sold under the trade name Aemcolo, is approved in the United States for treatment of travelers' diarrhea in some circumstances. [1] [2] [3]
Rifapentine in pregnant women has not been studied, but animal reproduction studies have resulted in fetal harm and were teratogenic. If rifapentine or rifampin are used in late pregnancy, coagulation should be monitored due to a possible increased risk of maternal postpartum hemorrhage and infant bleeding. [2]
The hope of a fixed-dose combination pill is to increase the likelihood that people will take all of three medications. [5] Also, if people forget to take one or two of their drugs, they might not then develop resistance to the remaining drugs.
It is influenced by traditional Chinese medicine. The other traditional medicine that is also practiced in Vietnam is traditional Chinese medicine (Trung Y), also known as Northern Herbology (Thuốc Bắc). [1] [2] Thuốc Nam is one of two kinds of folk remedies known to villagers, the other being the traditional exercise dưỡng sinh. [3] [4]
In total, the aircraft's armaments comprised: 120 20 mm rounds, 800 7.5 mm rounds, up to seven 200 kg bombs or other combinations (1–2 500 kg bombs in the belly, plus the two 200 kg in the wings). When flown with the maximum payload, this reduced the corresponding fuel load to only 1,000 liters. [17]
Other versions, such as a shortened ER with a range of 7,500 nautical miles (13,900 km; 8,600 mi), an all-cargo offering a maximum payload of 200,970 pounds (91,160 kg), and a Combi with a provision for ten freight pallets on the main deck, were proposed. Further growth of the aircraft was also foreseen, such as the MD-11 Advanced. [4]