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Osteoarthritis commonly affects the hands, feet, spine, and the large weight-bearing joints, such as the hips and knees, although in theory, any joint in the body can be affected. As osteoarthritis progresses, movement patterns (such as gait), are typically affected. [1] Osteoarthritis is the most common cause of a joint effusion of the knee. [15]
One of the main triggers of bone erosion in the joints in rheumatoid arthritis is inflammation of the synovium (lining of the joint capsule), caused in part by the production of pro-inflammatory cytokines and receptor activator of nuclear factor kappa B ligand (RANKL), a cell surface protein present in Th17 cells and osteoblasts. [71]
Arthritis is a form of arthropathy that involves inflammation of one or more joints, [3] [4] while the term arthropathy may be used regardless of whether there is inflammation or not. Joint diseases can be classified as follows: [citation needed] Arthritis; Infectious arthritis; Septic arthritis (infectious) Tuberculosis arthritis; Reactive ...
Arthritis comes in several different forms, including osteoarthritis (the most common type of arthritis and happens when bones become brittle due to age), rheumatoid arthritis (which happens when ...
The knee is one of the joints most commonly affected by osteoarthritis. [2] Cartilage in the knee may begin to break down after sustained stress, leaving the bones of the knee rubbing against each other and resulting in osteoarthritis. [7] Nearly a third of US citizens are affected by osteoarthritis of the knee by age 70. [8]
Rheumatism [2] / ˈ r uː m ə t ɪ z əm / or rheumatic disorders are conditions causing chronic, often intermittent pain affecting the joints or connective tissue. [3] Rheumatism does not designate any specific disorder, but covers at least 200 different conditions, including arthritis and "non-articular rheumatism", also known as "regional pain syndrome" or "soft tissue rheumatism".
When the structures outside the joint are affected, the term "false ankylosis" has been used in contradistinction to "true ankylosis", in which the disease is within the joint. When inflammation has caused the joint-ends of the bones to be fused together, the ankylosis is termed osseous or complete and is an instance of synostosis. Excision of ...
The causes of arthralgia are varied and range, from a joints perspective, from degenerative and destructive processes such as osteoarthritis and sports injuries to inflammation of tissues surrounding the joints, such as bursitis. [5] These might be triggered by other things, such as infections or vaccinations. [6]
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