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Mathematically, positive feedback is defined as a positive loop gain around a closed loop of cause and effect. [1][3] That is, positive feedback is in phase with the input, in the sense that it adds to make the input larger. [4][5] Positive feedback tends to cause system instability. When the loop gain is positive and above 1, there will ...
The Hodgkin cycle represents a positive feedback loop in which an initial membrane depolarization leads to uncontrolled deflection of the membrane potential to near V Na. The initial depolarization must reach or surpass a certain threshold in order to activate voltage-gated Na + channels. The opening of Na + channels allows Na + inflow, which ...
A vicious circle (or cycle) is a complex chain of events that reinforces itself through a feedback loop, with detrimental results. [1] It is a system with no tendency toward equilibrium (social, economic, ecological, etc.), at least in the short run. Each iteration of the cycle reinforces the previous one, in an example of positive feedback.
The interaction between the two types of loops is evident in mitosis. While positive feedback initiates mitosis, a negative feedback loop promotes the inactivation of the cyclin-dependent kinases by the anaphase-promoting complex. This example clearly shows the combined effects that positive and negative feedback loops have on cell-cycle ...
Na + channels both open and close more quickly than K + channels, producing an influx of positive charge (Na +) toward the beginning of the action potential and an efflux (K +) toward the end. Ligand-gated sodium channels, on the other hand, create the change in the membrane potential in the first place, in response to the binding of a ligand ...
A feedback loop where all outputs of a process are available as causal inputs to that process. Feedback occurs when outputs of a system are routed back as inputs as part of a chain of cause-and-effect that forms a circuit or loop. [1] The system can then be said to feed back into itself. The notion of cause-and-effect has to be handled ...
Shock is the state of insufficient blood flow to the tissues of the body as a result of problems with the circulatory system. [1][2] Initial symptoms of shock may include weakness, fast heart rate, fast breathing, sweating, anxiety, and increased thirst. [1] This may be followed by confusion, unconsciousness, or cardiac arrest, as complications ...
Transcription translation feedback loop. Transcription-translation feedback loop (TTFL) is a cellular model for explaining circadian rhythms in behavior and physiology. Widely conserved across species, the TTFL is auto-regulatory, in which transcription of clock genes is regulated by their own protein products.