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  2. RNA - Wikipedia

    en.wikipedia.org/wiki/RNA

    Initiation of transcription begins with the binding of the enzyme to a promoter sequence in the DNA (usually found "upstream" of a gene). The DNA double helix is unwound by the helicase activity of the enzyme. The enzyme then progresses along the template strand in the 3’ to 5’ direction, synthesizing a complementary RNA molecule with ...

  3. RNA-Seq - Wikipedia

    en.wikipedia.org/wiki/RNA-Seq

    RNA selection/depletion: To analyze signals of interest, the isolated RNA can either be kept as is, enriched for RNA with 3' polyadenylated (poly(A)) tails to include only eukaryotic mRNA, depleted of ribosomal RNA (rRNA), and/or filtered for RNA that binds specific sequences (RNA selection and depletion methods table, below). RNA molecules ...

  4. Transcription (biology) - Wikipedia

    en.wikipedia.org/wiki/Transcription_(biology)

    Transcription is the process of copying a segment of DNA into RNA for the purpose of gene expression. Some segments of DNA are transcribed into RNA molecules that can encode proteins, called messenger RNA (mRNA). Other segments of DNA are transcribed into RNA molecules called non-coding RNAs (ncRNAs). Both DNA and RNA are nucleic acids, which ...

  5. Central dogma of molecular biology - Wikipedia

    en.wikipedia.org/wiki/Central_dogma_of_molecular...

    A second version of the central dogma is popular but incorrect. This is the simplistic DNARNA → protein pathway published by James Watson in the first edition of The Molecular Biology of the Gene (1965). Watson's version differs from Crick's because Watson describes a two-step (DNARNA and RNA → protein) process as the central ...

  6. RNA-based evolution - Wikipedia

    en.wikipedia.org/wiki/RNA-based_evolution

    RNA served as a blueprint for genetic material and was the catalyst to multiply said blueprint. Currently RNA acts by forming proteins. protein enzymes carry out catalytic reactions. RNAs are critical in gene expression and that gene expression depends on mRNA, rRNA, and tRNA. [15] There is a relationship between protein and RNAs.

  7. Non-coding RNA - Wikipedia

    en.wikipedia.org/wiki/Non-coding_RNA

    The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene. Abundant and functionally important types of non-coding RNAs include transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as small RNAs such as microRNAs , siRNAs , piRNAs , snoRNAs , snRNAs , exRNAs , scaRNAs and the long ncRNAs such as ...

  8. Gene - Wikipedia

    en.wikipedia.org/wiki/Gene

    [1] [2] [3] During gene expression (the synthesis of RNA or protein from a gene), DNA is first copied into RNA. RNA can be directly functional or be the intermediate template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next.

  9. Ribosomal DNA - Wikipedia

    en.wikipedia.org/wiki/Ribosomal_DNA

    The ribosomal DNA (abbreviated rDNA) consists of a group of ribosomal RNA encoding genes and related regulatory elements, and is widespread in similar configuration in all domains of life. The ribosomal DNA encodes the non-coding ribosomal RNA , integral structural elements in the assembly of ribosomes , its importance making it the most ...