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Bacteriophages are among the most common and diverse entities in the biosphere. [2] Bacteriophages are ubiquitous viruses, found wherever bacteria exist. It is estimated there are more than 10 31 bacteriophages on the planet, more than every other organism on Earth, including bacteria, combined. [3]
Bacteriophages , potentially the most numerous "organisms" on Earth, are the viruses of bacteria (more generally, of prokaryotes [1]). Phage ecology is the study of the interaction of bacteriophages with their environments .
The dominant hosts for viruses in the ocean are marine microorganisms, such as bacteria. [14] Bacteriophages are harmless to plants and animals, and are essential to the regulation of marine and freshwater ecosystems [91] are important mortality agents of phytoplankton, the base of the foodchain in aquatic environments. [92]
Bacteriophages are bacterial viruses, evolved to infect bacterial cells. To do that, phages must use characteristic structures at cell surfaces (receptors), and to propagate they need appropriate molecular tools inside the cells. Bacteria are prokaryotes, and their cells differ substantially from eukaryotes, including humans or animals. [114]
To infect a host cell, the virus must first inject its own nucleic acid into the cell through the plasma membrane and (if present) the cell wall. The virus does so by either attaching to a receptor on the cell's surface or by simple mechanical force. The binding is due to electrostatic interactions and is influenced by pH and the presence of ions.
In a 1945 study by Demerec and Fano, [4] T7 was used to describe one of the seven phage types (T1 to T7) that grow lytically on Escherichia coli. [5] Although all seven phages were numbered arbitrarily, phages with odd numbers, or T-odd phages, were later discovered to share morphological and biochemical features that distinguish them from T-even phages. [6]
Several bacteriophages contain toxin genes that become incorporated into the host bacteria genome through infection and render the bacteria toxic. [9] Many well known bacterial toxins are produced from specific strains of the bacteria species that have obtained toxigenicity through lysogenic conversion, pseudolysogeny, or horizontal gene ...
Bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, [63] and the deep portions of Earth's crust. Bacteria also live in symbiotic and parasitic relationships with plants and animals.