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Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Doxylamine succinate is the active ingredient in many over-the-counter sleep aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
While pyridoxine/doxylamine, a combination of vitamin B 6 and doxylamine, is effective in nausea and vomiting of pregnancy, [48] some have questioned its effectiveness in HG. [49] Ondansetron may be beneficial, however, there are some concerns regarding an association with cleft palate, [50] and there is little high-quality data. [46]
A woman with lower levels in her blood outside of pregnancy may be at a higher risk of developing severe morning sickness in pregnancy, known as HG, researchers said. HG can lead to prolonged ...
Pyridoxine (PN) [4] is a form of vitamin B 6 found commonly in food and used as a dietary supplement.As a supplement it is used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning. [5]
Nausea can be caused by weight loss drugs, pregnancy, food poisoning, migraines. Doctors share home remedies for nausea, including ginger and peppermint.
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