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Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. [4] It is taken by mouth or by injection into a vein. [4] It begins working within an ...
The volume of distribution of cimetidine is 0.8 L/kg in adults and 1.2 to 2.1 L/kg in children. [6] Its plasma protein binding is 13 to 25% and is said to be without pharmacological significance. [ 6 ] [ 7 ] Cimetidine undergoes relatively little metabolism , with 56 to 85% excreted unchanged. [ 7 ]
Ranitidine was introduced in 1981, and was the world's biggest-selling prescription drug by 1987. [132] Subsequently, it was largely superseded by the more effective proton-pump inhibitor (PPI) class of drugs, with omeprazole becoming the biggest-selling drug for many years.
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In single-dose scenarios, the patient's body weight and the drug's recommended dose per kilogram are used to determine a safe one-time dose. If multiple doses of treatment are needed in a day, the physician must take into account information regarding the total amount of the drug which is safe to use in one day, and how that should be broken up ...
Close to 40% of adults who are 50+ who don’t have kids say it just didn’t happen and over 30% say they didn’t find the right partner. Younger adults, however, say they want to focus on their ...
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