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Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. [4] It is taken by mouth or by injection into a vein. [4] It begins working within an ...
The volume of distribution of cimetidine is 0.8 L/kg in adults and 1.2 to 2.1 L/kg in children. [6] Its plasma protein binding is 13 to 25% and is said to be without pharmacological significance. [ 6 ] [ 7 ] Cimetidine undergoes relatively little metabolism , with 56 to 85% excreted unchanged. [ 7 ]
In single-dose scenarios, the patient's body weight and the drug's recommended dose per kilogram are used to determine a safe one-time dose. If multiple doses of treatment are needed in a day, the physician must take into account information regarding the total amount of the drug which is safe to use in one day, and how that should be broken up ...
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Ranitidine was introduced in 1981, and was the world's biggest-selling prescription drug by 1987. [132] Subsequently, it was largely superseded by the more effective proton-pump inhibitor (PPI) class of drugs, with omeprazole becoming the biggest-selling drug for many years.
Close to 40% of adults who are 50+ who don’t have kids say it just didn’t happen and over 30% say they didn’t find the right partner. Younger adults, however, say they want to focus on their ...
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