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As a blood pressure medication, spironolactone is usually prescribed at a dose of 25 milligrams a day. For acne, the dosage is higher: it’s often started at 50 mg and then titrated up to 100 mg ...
The effectiveness of spironolactone in the treatment of both acne and hirsutism appears to be dose-dependent, with higher doses being more effective than lower doses. [ 85 ] [ 96 ] [ 97 ] However, higher doses also have greater side effects, such as menstrual irregularities .
If hormonal acne is a skin concern, you may have heard of Spironolactone. Here, a dermatologist explains what you need to know about Spironolactone. Spironolactone: 11 things a dermatologist wants ...
Spironolactone: Spironolactone is used to treat high blood pressure but is also prescribed off-label for treating acne in women. Spironolactone reduces the amount of androgen hormones in your body ...
It has been widely stated that the menstrual irregularities associated with spironolactone are due to its progestogenic activity, and animal studies, both in rabbits and rhesus monkeys, have shown clear progestogenic effects of spironolactone. [118] However, the dosages of spironolactone used in animals to produce progestogenic effects were ...
The effectiveness of spironolactone for acne appears to be dose-dependent. [116] High-dose cyproterone acetate alone reportedly decreases acne symptoms in women by 75 to 90% within three months. [127] It is usually combined with an estrogen to avoid menstrual irregularities and estrogen deficiency. [128]
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