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[145] [146] [147] However, a 2017 hybrid systematic review found that the incidence of depression in women treated with spironolactone for acne was less than 1%. [63] Likewise, a 10-year observational study found that the incidence of depression in 196 transgender women taking high-dose spironolactone in combination with an estrogen was less ...
[63] [64] [65] One study compared placebo and dosages of spironolactone of 50, 100, 150, and 200 mg/day in the treatment of acne in women and observed progressive increases in response rates up to the 200 mg/day dosage.
One phase 3 clinical trial, published in The BMJ last year, followed 400 women taking either spironolactone or a placebo for 24 weeks. Side effects were slightly more common in women who got the ...
3. Spironolactone. Another androgen- and DHT-targeting treatment that can work for women is spironolactone. It’s sometimes prescribed off-label to treat hair loss that occurs due to polycystic ...
The American College of Obstetrics and Gynecology (ACOG) approves of HRT for symptomatic relief of menopausal symptoms, [14] and advocates its use beyond the age of 65 in appropriate scenarios. [15] The North American Menopause Society (NAMS) 2016 annual meeting mentioned that HRT may have more benefits than risks in women before the age of 60 ...
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This use of the drug is off-label, however, not having been approved by the Food and Drug Administration and without data on long-term effects of this use. [needs update] [18] They are also sometimes used as alternatives to antiandrogens like spironolactone and cyproterone acetate for suppressing testosterone production in transgender women.
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