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  2. Santiago Luis Polanco Rodríguez - Wikipedia

    en.wikipedia.org/wiki/Santiago_Luis_Polanco...

    Santiago Luis Polanco-Rodríguez (born June 16, 1961) is a Dominican American former drug dealer considered to be the first mass marketer of crack cocaine in United States. He is also known by his street name, "Yayo". [1]

  3. Crack cocaine - Wikipedia

    en.wikipedia.org/wiki/Crack_cocaine

    A woman smoking crack cocaine in San Francisco, California, in December 2005. Crack cocaine is commonly used as a recreational drug. Effects of crack cocaine include euphoria, [11] supreme confidence, [12] loss of appetite, [11] insomnia, [11] alertness, [11] increased energy, [11] a craving for more cocaine, [12] and potential paranoia (ending ...

  4. History and culture of substituted amphetamines - Wikipedia

    en.wikipedia.org/wiki/History_and_culture_of...

    Amphetamine was first synthesized in 1887 in Germany by Romanian chemist, Lazăr Edeleanu, who named the drug phenylisopropylamine. [4] [3] [18] [2] This concoction was one of a series of compounds related to the plant derivative ephedrine, which had been isolated from the Chinese ephedra plant that same year by Nagai Nagayoshi. [6]

  5. Cocaine - Wikipedia

    en.wikipedia.org/wiki/Cocaine

    A woman smoking crack cocaine "Rocks" of crack cocaine. Crack is usually smoked in a glass pipe, and once inhaled, it passes from the lungs directly to the central nervous system, producing an almost immediate "high" that can be very powerful – this initial crescendo of stimulation is known as a "rush". This is followed by an equally intense ...

  6. History of smoking - Wikipedia

    en.wikipedia.org/wiki/History_of_smoking

    However, overproduction of cocaine powder in those islands drove the price down by as much as 80 percent. Confronted with falling profits for their illegal product, drug dealers decided to convert the powder to crack, a solid, smokable form of cocaine, that they could sell in smaller quantities to more people. It was cheap, simple to produce ...

  7. Crack epidemic in the United States - Wikipedia

    en.wikipedia.org/wiki/Crack_epidemic_in_the...

    Various paraphernalia used to smoke crack cocaine, including a homemade crack pipe made out of an empty plastic water bottle.. In a study done by Roland Fryer, Steven Levitt, and Kevin Murphy, a crack index was calculated using information on cocaine-related arrests, deaths, and drug raids, along with low birth rates and media coverage in the United States.

  8. List of drugs by year of discovery - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_by_year_of...

    The following is a table of drugs organized by their year of discovery. Naturally occurring chemicals in plants, including alkaloids, have been used since pre-history.In the modern era, plant-based drugs have been isolated, purified and synthesised anew.

  9. Raphael Mechoulam - Wikipedia

    en.wikipedia.org/wiki/Raphael_Mechoulam

    In 1963 Mechoulam began working on the components of the cannabis plant, from which hashish and marijuana are produced. Although cannabis had been the most widely used illegal drug in many parts of the world for centuries, its chemistry and biology were unknown, in contrast to morphine and cocaine, the two other common illegal drugs, which had ...