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Eosinophilic gastroenteritis (EG or EGE), also known as eosinophilic enteritis, [1] is a rare and heterogeneous condition characterized by patchy or diffuse eosinophilic infiltration of gastrointestinal (GI) tissue, first described by Kaijser in 1937.
An incompletely defined syndrome of inflammation related to the quality of the environment. Signs and symptoms include reduced absorptive capacity and reduced intestinal barrier function of the small intestine. It is widespread among children and adults in low- and middle-income countries. [2] Eosinophilic enteropathy
Signs and symptoms of enteritis are highly variable and vary based on the specific cause and other factors such as individual variance and stage of disease. Symptoms may include abdominal pain , cramping , diarrhea , [ 3 ] dehydration , fever , nausea , vomiting , and weight loss .
The classic triad of symptoms in APS-1 is hypoparathyroidism, adrenal insufficiency, and mucocutaneous candidiasis. The majority of APS-1 patients start showing symptoms early in childhood and gradually get worse as they get older. Usually, the first symptom to appear is candidiasis, which usually affects the nails or oral cavity.
When it comes to ileitis, the majority of cases are caused by an acute, self-limited form of lower right quadrant pain and/or diarrhea.However, other conditions, such as M. tuberculosis or vasculitis, can cause chronic, debilitating symptoms that are complicated by hemorrhage, obstructive symptoms, and/or extraintestinal manifestations.
Based on their causes, hypereosinophilias can be sorted into subtypes. However, cases of eosinophilia, which exhibit eosinophil counts between 500 and 1,500/μL, may fit the clinical criteria for, and thus be regarded as falling into, one of these hypereosinophilia categories: the cutoff of 1,500/μL between hypereosinophilia and eosinophilia is somewhat arbitrary.
This results in the signs and symptoms of pain, visible redness on endoscopy, and a natural history that may include stricturing. [3] Eosinophils are normally present in other parts of a healthy gastrointestinal tract, these white blood cells are not normally found in the esophagus of a healthy individual.
The main symptom of gastroenteritis is diarrhea. Other symptoms may include: [citation needed] Abdominal pain or cramping; Nausea; Vomiting; Low grade fever; Because of the symptoms of vomiting and diarrhea, people who have gastroenteritis can become dehydrated quickly. It is very important to watch for signs of dehydration. [1]