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In 1903, Nikolai K. Koltsov proposed that the shape of cells was determined by a network of tubules that he termed the cytoskeleton. The concept of a protein mosaic that dynamically coordinated cytoplasmic biochemistry was proposed by Rudolph Peters in 1929 [12] while the term (cytosquelette, in French) was first introduced by French embryologist Paul Wintrebert in 1931.
Cell metabolism is the process by which individual cells process nutrient molecules. Metabolism has two distinct divisions: catabolism , in which the cell breaks down complex molecules to produce energy and reducing power , and anabolism , in which the cell uses energy and reducing power to construct complex molecules and perform other ...
The cell body varies in size from 5–20 micrometers in diameter and contain 40–60 cell processes per cell, [4] with a cell to cell distance between 20–30 micrometers. [3] A mature osteocyte contains a single nucleus that is located toward the vascular side and has one or two nucleoli and a membrane. [ 5 ]
Heterotopic ossification is a process resulting in the formation of bone tissue that is often atypical, at an extraskeletal location. Calcification is often confused with ossification. Calcification is synonymous with the formation of calcium-based salts and crystals within cells and tissue.
In anatomy, a process (Latin: processus) is a projection or outgrowth of tissue from a larger body. [1] For instance, in a vertebra, a process may serve for muscle attachment and leverage (as in the case of the transverse and spinous processes), or to fit (forming a synovial joint), with another vertebra (as in the case of the articular processes). [2]
Light micrograph of a nidus consisting of osteoprogenitor cells that are displaying a prominent Golgi apparatus. The process of intramembranous ossification starts when a small group of adjacent MSCs begin to replicate and form a small, dense cluster of cells that is called a nidus. [a] Once a nidus has been formed the MSCs within it stop ...
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Another famous model is the so-called French flag model, developed in the sixties. [31] Improvements in computer performance in the twenty-first century enabled the simulation of relatively complex morphogenesis models. In 2020, such a model was proposed where cell growth and differentiation is that of a cellular automaton with
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