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The hepatitis C virus (HCV) [3] is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer ( hepatocellular carcinoma , abbreviated HCC) and lymphomas in humans.
Hepatitis A and hepatitis B can be prevented by vaccination. Effective treatments for hepatitis C are available but costly. [6] In 2013, about 1.5 million people died from viral hepatitis, most commonly due to hepatitis B and C. [6] East Asia, in particular Mongolia, is the region most affected. [6]
Chronic hepatitis C is defined as infection with the hepatitis C virus persisting for more than six months based on the presence of its RNA. [18] Chronic infections are typically asymptomatic during the first few decades, [ 18 ] and thus are most commonly discovered following the investigation of elevated liver enzyme levels or during a routine ...
Hepatitis B virus (HBV) is a partially ... Differences between genotypes affect the disease severity, course and likelihood of complications, and response to ...
HCV: hepatitis C virus: HD: Hodgkin disease Hemodialysis Huntington's disease: HDL: high-density lipoprotein: HDL-C: high-density lipoprotein-cholesterol HDN: hemolytic disease of the newborn: HDS: hemodynamically stable (i.e., not bleeding) HDU: high dependency unit: HDV: hepatitis D virus: HDW: Hemoglobin Distribution Width: H&E: hematoxylin ...
Hepatitis D is a defective virus that requires hepatitis B to replicate and is only found with hepatitis B co-infection. [17] In adults, hepatitis B infection is most commonly self-limiting, with less than 5% progressing to chronic state, and 20 to 30% of those chronically infected developing cirrhosis or liver cancer. [ 30 ]
The most common blood-borne diseases are hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV). [7] Exposure is possible through blood of an infected patient splashing onto mucous membranes; however, the greatest exposure risk was shown to occur during percutaneous injections performed for vascular access.
Hepatitis B virus replication. The life cycle of hepatitis B virus is complex. Hepatitis B is one of a few known pararetroviruses: non-retroviruses that still use reverse transcription in their replication process. The virus gains entry into the cell by binding to NTCP [51] on the surface and being endocytosed. Because the virus multiplies via ...
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