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Basophilia, as it is primarily a secondary condition, is treated by addressing the causative disease or disorder. The underlying condition will determine what treatment is appropriate. Specifically in cases of allergic reactions or associated with chronic inflammation, treating the underlying cause is critical to avoid further, potentially ...
Basophilic stippling, also known as punctate basophilia, is the presence of numerous basophilic granules that are dispersed through the cytoplasm of erythrocytes in a peripheral blood smear. They can be demonstrated to be RNA .
An abnormal increase in basophil granulocytes is therefore also described as basophilia. [2] The opposite of basophilic structures are acidophilic structures, also called eosinophilic. These structures contain many positive charges and are thus strongly stained by anionic dyes like eosin.
Basopenia (or basocytopenia) is a form of agranulocytosis associated with a deficiency of basophils. [1] It has been proposed as an indicator of ovulation. [2] It is difficult to detect without flow cytometry, because normal levels are so low. [3]
Basophils appear in many specific kinds of inflammatory reactions, particularly those that cause allergic symptoms. Basophils contain anticoagulant heparin, [8] which prevents blood from clotting too quickly. They also contain the vasodilator histamine, which promotes blood flow to tissues.
Differentiated (basophilic granules by light microscopy) and poorly differentiated cases; Majority are poorly differentiated. MPO negative by light microscopy; granules positive in a speckled pattern by electron microscopy.
Döhle bodies are light blue-gray, oval, basophilic, leukocyte inclusions located in the peripheral cytoplasm of neutrophils.They measure 1–3 μm in diameter. Not much is known about their formation, but they are thought to be remnants of the rough endoplasmic reticulum.
Necrobiosis is the physiological death of a cell, and can be caused by conditions such as basophilia, erythema, or a tumor. It is identified both with [1] and without necrosis. Necrobiotic disorders are characterized by presence of necrobiotic granuloma on histopathology.