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Addison's disease, also known as primary adrenal insufficiency, [4] is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal glands (adrenal cortex), causing adrenal insufficiency.
Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas.
In researching pernicious anemia, Addison in 1849 came across the changed "bronzed" appearance of the adrenal glands. [10] What is now called Addison's disease, sometimes called bronze skin disease, is the progressive destruction of the glands, resulting in adrenocortical hormone deficiency.
Addison’s disease is an autoimmune condition — affecting about one in 100,000 people — in which the body attacks its organs, ... or a darkening of the skin that can make people appear bronzed.
Addison's disease, or primary adrenal insufficiency, is an uncommon chronic illness characterized by insufficient production of cortisol and aldosterone by the adrenal glands. [17] Chronic primary adrenal insufficiency is typically characterized by an extended period of malaise, fatigue, anorexia, weight loss, joint and back pain, and skin ...
Adrenal crisis; Other names: Acute adrenal insufficiency, Addisonian crisis, Acute adrenal failure. [1]49-year-old male with an adrenal crisis. Appearance, showing lack of facial hair, dehydration, Queen Anne's sign (panel A), pale skin, muscular and weight loss, and loss of body hair (panel B).
Rosacea. What it looks like: Rosacea causes redness and thick skin on the face, usually clustered in the center.Easy flushing, a stinging sensation, and small, pus-filled pimples are other common ...
[N 5] Anemia often causes pallor and, in "Addison's anemia", a discolored appearance of the skin is normally to be expected, i.e. the opposite of the bronzed appearance usually seen in "Addison's adrenal insufficiency". Cope concluded: "There is no disease other than Addison's disease that could present a face that was "black and white" and at ...
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