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Nitric oxide sensing in plants is mediated by the N-end rule of proteolysis [61] [62] and controls abiotic stress responses such as flooding-induced hypoxia, [63] salt and drought stress. [64] [65] [66] Nitric oxide interactions have been found within signaling pathways of plant hormones such as auxin, [67] ethylene, [63] [68] [69] Abscisic ...
Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule. It helps modulate vascular tone , insulin secretion, airway tone, and peristalsis , and is involved in angiogenesis and neural development.
The changes elicited by ligand binding (or signal sensing) in a receptor give rise to a biochemical cascade, which is a chain of biochemical events known as a signaling pathway. When signaling pathways interact with one another they form networks, which allow cellular responses to be coordinated, often by combinatorial signaling events. [2]
A more complex signal transduction pathway is the MAPK/ERK pathway, which involves changes of protein–protein interactions inside the cell, induced by an external signal. Many growth factors bind to receptors at the cell surface and stimulate cells to progress through the cell cycle and divide .
The first retrograde signaling pathways discovered in yeast is the RTG pathway. [ 10 ] [ 11 ] The RTG pathway plays an important role in maintaining the metabolic homeostasis of yeast. [ 11 ] Under limited resources the mitochondria must maintain a balance of glutamate for the citric acid cycle . [ 12 ]
The three gases have similar features and, in theory, participate in shared signaling pathways, although their actions can either be synergistic or antagonistic. [ 5 ] [ 6 ] Nitric oxide and hydrogen sulfide are highly reactive with numerous molecular targets, whereas carbon monoxide is relatively stable and metabolically inert predominately ...
The basic unit of the Reactome database is a reaction; reactions are then grouped into causal chains to form pathways [115] The Reactome data model allows us to represent many diverse processes in the human system, including the pathways of intermediary metabolism, regulatory pathways, and signal transduction, and high-level processes, such as ...
Gaseous signaling molecules are gaseous molecules that are either synthesized internally (endogenously) in the organism, tissue or cell or are received by the organism, tissue or cell from outside (say, from the atmosphere or hydrosphere, as in the case of oxygen) and that are used to transmit chemical signals which induce certain physiological or biochemical changes in the organism, tissue or ...