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Now researchers at private biotech companies like Conception Bio and Gameto are racing to see if they can develop this in vitro gametogenesis (IVG) technology as a way to safely enable post ...
The very concept of in vitro gametogenesis (IVG) sounds space age. It aims to take somatic cells (“normal” cells) and turn them into gametes (reproductive cells).
Gametogenesis is a biological process by which diploid or haploid precursor cells undergo cell division and differentiation to form mature haploid gametes. Depending on the biological life cycle of the organism , gametogenesis occurs by meiotic division of diploid gametocytes into various gametes, or by mitosis.
In vitro spermatogenesis is the process of creating male gametes (spermatozoa) outside of the body in a culture system. The process could be useful for fertility preservation, infertility treatment and may further develop the understanding of spermatogenesis at the cellular and molecular level.
In vitro fertilisation (IVF) is a process of fertilisation in which an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating a woman's ovulatory process , then removing an ovum or ova (egg or eggs) from her ovaries and enabling a man's sperm to fertilise them in a culture medium in a laboratory.
Upon in vitro development, blastoids generate analogs of the primitive endoderm cells, thus comprising analogs of the three founding cell types of the conceptus (epiblast, trophoblast and primitive endoderm), and recapitulate aspects of implantation on being introduced into the uterus of a compatible female. [4]
The first pregnancy achieved through in vitro human fertilisation of a human oocyte was reported in The Lancet from the Monash University team of Carl Wood, John Leeton and Alan Trounson [8] in 1973, although it lasted only a few days and would today be called a biochemical pregnancy.
They founded the first IVF programme for infertile patients and trained other scientists in their techniques. Edwards was the founding editor-in-chief of Human Reproduction in 1986. [9] In 2010, he was awarded the Nobel Prize in Physiology or Medicine "for the development of in vitro fertilization". [10] [11]