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Implementation research is the systematic study of methods that support the application of research findings and other evidence-based knowledge into policy and practice. [1] It aims to understand the most effective pathways from research to practical application, particularly in areas such as health, education, psychology and management. [ 2 ]
A type of research study that tests how well new medical approaches work in people. These studies test new methods of screening, prevention, diagnosis, or treatment of a disease. Also called a clinical trial. (NCI) A clinical trial is a research study to answer specific questions about vaccines or new therapies or new ways of using known ...
A quasi-experiment is an empirical interventional study used to estimate the causal impact of an intervention on target population without random assignment.Quasi-experimental research shares similarities with the traditional experimental design or randomized controlled trial, but it specifically lacks the element of random assignment to treatment or control.
A clinical control group can be a placebo arm or it can involve an old method used to address a clinical outcome when testing a new idea. For example in a study released by the British Medical Journal, in 1995 studying the effects of strict blood pressure control versus more relaxed blood pressure control in diabetic patients, the clinical control group was the diabetic patients that did not ...
The United States Department of Health and Human Services (HHS) defines a human research subject as a living individual about whom a research investigator (whether a professional or a student) obtains data through 1) intervention or interaction with the individual, or 2) identifiable private information (32 CFR 219.102).
A megastudy or mega-study is a research study in which a large number of different treatments or interventions are tested at the same time, on the same sample or similar samples, using a common outcome measure, and using the same experimental protocol. [1] [2] [3] This research design ensures the outcomes across interventions are comparable.
In design of experiments, single-subject curriculum or single-case research design is a research design most often used in applied fields of psychology, education, and human behaviour in which the subject serves as his/her own control, rather than using another individual/group. Researchers use single-subject design because these designs are ...
ITT analysis is intended to avoid various misleading artifacts that can arise in intervention research such as non-random attrition of participants from the study or crossover. ITT is also simpler than other forms of study design and analysis, because it does not require observation of compliance status for units assigned to different ...