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  2. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    As you can see, vardenafil and avanafil work for about the same amount of time — and slightly longer than sildenafil. But tadalafil is by far the longest-lasting of the four ED medications ...

  3. Vardenafil - Wikipedia

    en.wikipedia.org/wiki/Vardenafil

    The common, adverse drug reactions (side effects) are the same as with other PDE5 inhibitors. The frequent vardenafil-specific side-effect is nausea; the infrequent side effects are abdominal pain, back pain, photosensitivity, abnormal vision, eye pain, facial edema, hypotension, palpitation, tachycardia, arthralgia, myalgia, rash, itch, and priapism.

  4. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

    www.aol.com/4-common-ed-pills-weighing-141800609...

    Vardenafil is the active ingredient in Levitra, and the FDA approved it in 2003. It’s similar to sildenafil but lasts longer — research suggests it provides better blood flow and stronger ...

  5. 4 Surprising Uses of Viagra (Including What It Was Really ...

    www.aol.com/4-surprising-uses-viagara-including...

    Viagra (Sildenafil): Uses, Benefits and Side Effects. Whether you’re a senior in high school or a senior-living resident, you’ve likely heard of Viagra (sildenafil) — the original medication ...

  6. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]

  7. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  8. What Is the Safest ED Medication? - AOL

    www.aol.com/safest-ed-medication-105700669.html

    Vardenafil. The active ingredient in Levitra, vardenafil provides relief from ED for four to five hours. Avanafil. Sold as Stendra, avanafil is a newer treatment that provides relief from ED for ...

  9. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    This allows for a longer therapeutic window and is therefore often a more convenient drug than others with a shorter therapeutic window. Tadalafil is more bioavailable (80%) than sildenafil (40%) and vardenafil (15%) but it has a slow absorption, or about 2 hours compared to 50 minutes of sildenfil. Vardenafil is most known for its potency. [24]

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