Search results
Results from the WOW.Com Content Network
Carnitine palmitoyltransferase II deficiency, sometimes shortened to CPT-II or CPT2, is an autosomal recessively inherited genetic metabolic disorder characterized by an enzymatic defect that prevents long-chain fatty acids from being transported into the mitochondria for utilization as an energy source. The disorder presents in one of three ...
12896 Ensembl ENSG00000157184 ENSMUSG00000028607 UniProt P23786 P52825 RefSeq (mRNA) NM_000098 NM_001330589 NM_009949 RefSeq (protein) NP_000089 NP_001317518 NP_034079 Location (UCSC) Chr 1: 53.2 – 53.21 Mb Chr 4: 107.76 – 107.78 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carnitine O-palmitoyltransferase 2, mitochondrial is an enzyme that in humans is encoded by the CPT2 ...
Carnitine, a natural substance acquired mostly through the diet, is used by cells to process fats and produce energy. People with this disorder have a faulty enzyme, carnitine palmitoyltransferase I , that prevents these long-chain fatty acids from being transported into the mitochondria to be broken down.
Carnitine-acylcarnitine translocase deficiency has an autosomal recessive pattern of inheritance. Carnitine-acylcarnitine translocase deficiency is a rare, autosomal recessive metabolic disorder that prevents the body from converting long-chain fatty acids into energy, particularly during periods without food. [ 1 ]
Carnitine O-palmitoyltransferase (also called carnitine palmitoyltransferase) is a mitochondrial transferase enzyme (EC 2.3.1.21) involved in the metabolism of palmitoylcarnitine into palmitoyl-CoA. A related transferase is carnitine acyltransferase .
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
The presentation of patient with SPCD can be incredibly varied, from asymptomatic to lethal cardiac manifestations. [5] Early cases were reported with liver dysfunction, muscular findings (weakness and underdevelopment), hypoketotic hypoglycemia, cardiomegaly, cardiomyopathy and marked carnitine deficiency in plasma and tissues, combined with increased excretion in urine. [5]
CPT2 may refer to: Carnitine palmitoyltransferase II , an important metabolic enzyme. Carnitine palmitoyltransferase II deficiency , a condition that prevents the body from converting certain fats into energy