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These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Common side effects include sedation, fatigue, weight gain, constipation, and dry mouth. [11] Other side effects include low blood pressure with standing, seizures, a prolonged erection, high blood sugar, tardive dyskinesia, and neuroleptic malignant syndrome. [11] In older people with dementia, its use increases the risk of death. [11]
[4] [3] Although atypical antipsychotics are thought to be safer than typical antipsychotics, they still have severe side effects, including tardive dyskinesia (a serious movement disorder), neuroleptic malignant syndrome, and increased risk of stroke, sudden cardiac death, blood clots, and diabetes. Significant weight gain may occur. Critics ...
Weight gain. Some side effects, such as weight gain, occur more frequently with certain types of antidepressant medication. Switching to a new type of antidepressant may help reverse any weight ...
Some atypicals are associated with considerable weight gain, diabetes and the risk of metabolic syndrome. [110] Unwanted side effects cause people to stop treatment, resulting in relapses. [111] Risperidone (atypical) has a similar rate of extrapyramidal symptoms to haloperidol (typical). [110]
Treatment guidelines from the National Institute of Health and Clinical Excellence [37] recommend against the use of SSRIs in this disorder. Those from the American Psychiatric Association note that SSRIs confer no advantage regarding weight gain, but that they may be used for the treatment of co-existing depression, anxiety, or OCD. [38]
In humans the effects of excess serotonin were first noted in 1960 in patients receiving an MAOI and tryptophan. [54] The syndrome is caused by increased serotonin in the CNS. [6] It was originally suspected that agonism of 5-HT 1A receptors in central grey nuclei and the medulla oblongata was responsible for the development of the syndrome. [55]
For anyone who goes on a weight loss medication, “if they stay active, they exercise, they maintain good nutrition, that all can go a long way to preventing muscle loss and preserving muscle ...