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Alka-Seltzer is an effervescent antacid and pain reliever owned by Bayer since 1978. First marketed by the Dr. Miles Medicine Company of Elkhart, Indiana , United States , Alka-Seltzer contains three active ingredients: aspirin (acetylsalicylic acid or ASA), sodium bicarbonate , and anhydrous citric acid . [ 1 ]
Effervescent tablets are tablets which are designed to dissolve in water, and then release carbon dioxide. [21] [22] [23] Common ingredients include citric acid and sodium bicarbonate, which react when in contact with water to produce carbon dioxide. Effervescent antacids may also contain aspirin, [24] sodium carbonate, or tartaric acid. [25]
Effervescent tablets mostly come in capsules constructed for these tablets. They may contain an anti-bacterial coating and are water resistant. The cap contains a little spring-like spiral, which helps keeping the tablets in place during transportation and prevents them from breaking. The cap also contains little balls made out of silica gel. [18]
The company is known for inventing products such as Alka-Selzer and One-A-Day vitamins. [1] Miles operated as an independent firm from 1884 until 1979 and as a wholly owned subsidiary of Bayer AG from 1979 until 1995. At the company's peak in the 1960s and 1970s, it employed 3,300 people and produced more than two dozen products. [2]
It can be found in the milk minicontainers used with coffee machines. The compound is the product of antacids, such as Alka-Seltzer, when they are dissolved in water. [citation needed] The pH range of a solution of 5 g/100 ml water at 25 °C is 7.5 to 9.0.
Approved indication for dihydrocodeine is the management of moderate to moderately severe pain as well as coughing and shortness of breath. As is the case with other drugs in this group, the antitussive dose tends to be less than the analgesic dose, and dihydrocodeine is a powerful cough suppressant like all other members of the immediate codeine family (see below) and their cousins ...
These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
These effects are mainly due to the properties of the potassium ion—sodium bromide tastes salty at any concentration. In high concentration, potassium bromide strongly irritates the gastric mucous membrane, causing nausea and sometimes vomiting (a typical effect of all soluble potassium salts).
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