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Leukocyte esterase (LE) is an esterase (a type of enzyme) produced by leukocytes (white blood cells). A leukocyte esterase test (LE test) is a urine test for the presence of white blood cells and other abnormalities associated with infection. White blood cells in the urine can indicate a urinary tract infection (UTI). Positive test results may ...
Reference ranges for urine tests are described below: ... 0 / negative [2] White blood cells (WBCs) 0 [2] 2 [2] pH: ... Leukocytes: n/a: 0 / negative [2] See also
A negative dipstick test does not exclude bacteriuria, as not all bacteria which can colonise the urinary tract are nitrate-reducing. The leukocyte esterase test indirectly detects the presence of leukocytes (white blood cells) in urine which can be associated with a urinary tract infection. In the elderly, the leukocyte esterase test is often ...
Leukocyte esterase, an enzyme found in granulocytes, is measured to estimate the concentration of white blood cells. [53] The action of the enzyme on chemicals in the test pad ends in the creation of a purple azo dye . [ 54 ]
In straightforward cases, a diagnosis may be made and treatment given based on symptoms alone without further laboratory confirmation. [4] In complicated or questionable cases, it may be useful to confirm the diagnosis via urinalysis, looking for the presence of urinary nitrites, white blood cells (leukocytes), or leukocyte esterase. [54]
The urine test strip test for white blood cells detects leukocyte esterase, which is present in azurophilic granules of monocytes and granulocytes (neutrophilic, eosinophilic and basophilic). Bacteria, lymphocytes and epithelial cells from the genitourinary tract do not contain esterases. [21]
Pyuria is the condition of urine containing white blood cells or pus.Defined as the presence of 6-10 or more neutrophils per high power field of unspun, voided mid-stream urine, it can be a sign of a bacterial urinary tract infection.
For example, if the blood sample is not processed immediately after it is collected, continued cellular metabolism by leukocytes (also known as white blood cells) may result in an increase in the HCO − 3 concentration, and result in a corresponding mild reduction in the anion gap. In many situations, alterations in renal function (even if ...