Search results
Results from the WOW.Com Content Network
The chromosomal location of BRCA1 was discovered by Mary-Claire King's team at UC Berkeley in 1990. [21] After an international race to refine the precise location of BRCA1, [22] the gene was cloned in 1994 by scientists at University of Utah, National Institute of Environmental Health Sciences (NIEHS) and Myriad Genetics.
Women with deleterious mutations in either the BRCA1 or BRCA2 genes have a high risk of developing breast and/or ovarian cancer. Because different studies look at different populations, and because different types of mutations have somewhat different risks, the risk is best expressed as a range, rather than a single number. [9]: 89–111
BRCA1-A complex subunit BRE is a protein that in humans is encoded by the BRE gene. [5] [6] [7] Repair of DNA damage. BRE, the protein product of the BRE (gene), is a ...
The horse genome is larger than the dog genome, but smaller than the human genome or the bovine genome. [2] It encompasses 31 pairs of autosomes and one sex chromosome pair. [3] As horses share over 90 hereditary diseases similar to those found in humans, the sequencing of the horse genome has potential applications to both equine and human ...
The list of organisms by chromosome count describes ploidy or numbers of chromosomes in the cells of various plants, animals, protists, and other living organisms.This number, along with the visual appearance of the chromosome, is known as the karyotype, [1] [2] [3] and can be found by looking at the chromosomes through a microscope.
ATM activates (phosphorylates) CHEK2 and FANCD2 [22] CHEK2 phosphorylates BRCA1. [23] Ubiquinated FANCD2 complexes with BRCA1 and RAD51. [24] The PALB2 protein acts as a hub, [25] bringing together BRCA1, BRCA2 and RAD51 at the site of a DNA double-strand break, and also binds to RAD51C, a member of the RAD51 paralog complex RAD51B-RAD51C ...
A hinny is a domestic equine hybrid, the offspring of a male horse (a stallion) and a female donkey (a jenny). It is the reciprocal cross to the more common mule, which is the product of a male donkey (a jack) and a female horse (a mare).
ATM activates (phosphorylates) CHEK2 and FANCD2 [10] CHEK2 phosphorylates BRCA1. [11] Ubiquinated FANCD2 complexes with BRCA1 and RAD51 . [ 12 ] The PALB2 protein acts as a hub, [ 13 ] bringing together BRCA1, BRCA2 and RAD51 at the site of a DNA double-strand break, and also binds to RAD51C, a member of the RAD51 paralog complex RAD51B ...