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Additional drugs affected by grapefruit juice include, but are not limited to: Some statins, including atorvastatin (Lipitor), [60] lovastatin (Mevacor), and simvastatin (Zocor, Simlup, Simcor, Simvacor) [61] In contrast, pravastatin (Pravachol), [60] fluvastatin (Lescol), and rosuvastatin (Crestor) [61] are unaffected by grapefruit.
Still, says Peterson, "most people won't have issues unless they eat large quantities of grapefruit, drink more than one liter per day of grapefruit juice, or consistently eat or drink grapefruit.
Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. [6] It is recommended to be used together with dietary changes, exercise, and weight loss. [ 6 ]
Furanocoumarins in grapefruit juice (i.e. bergamottin and dihydroxybergamottin) inhibit the cytochrome P450 enzyme CYP3A4, which is involved in the metabolism of most statins (however, it is a major inhibitor of only lovastatin, simvastatin, and to a lesser degree, atorvastatin) and some other medications [129] (flavonoids (i.e. naringin) were ...
Grapefruit is famously juicy and tangy, with its yellow, pink or ruby flesh reaching peak ripeness in the winter months. The citrus gets a lot of buzz during cold and flu season and weight-loss ...
Grapefruit. It can interact with some antibiotics such as erythromycin, according to the National Capital Poison Center. Check the label of your antibiotic.
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
Diabetes, a condition where blood glucose levels cannot be controlled, affects more than 10% of the adult population worldwide, and more than 90% of those have type 2 diabetes.
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