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  2. FLAG (chemotherapy) - Wikipedia

    en.wikipedia.org/wiki/FLAG_(chemotherapy)

    FLAG is a chemotherapy regimen used for relapsed and refractory acute myeloid leukemia (AML). [1] The acronym incorporates the three primary ingredients of the regimen: . Fludarabine: an antimetabolite that, while not active toward AML, increases formation of an active cytarabine metabolite, ara-CTP, in AML cells;

  3. Cytarabine - Wikipedia

    en.wikipedia.org/wiki/Cytarabine

    Cytarabine, also known as cytosine arabinoside (ara-C), is a chemotherapy medication used to treat acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML), and non-Hodgkin's lymphoma. [2] It is given by injection into a vein, under the skin, or into the cerebrospinal fluid. [2]

  4. CD135 - Wikipedia

    en.wikipedia.org/wiki/CD135

    In July 2023, quizartinib (Vanflyta) was also approved for the treatment of newly diagnosed AML with FLT3 internal tandem duplication (ITD)-positive, as detected by an FDA-approved test. [14] Precisely, it should be used with standard cytarabine and anthracycline induction and cytarabine consolidation, and as maintenance monotherapy following ...

  5. Daunorubicin/cytarabine - Wikipedia

    en.wikipedia.org/wiki/Daunorubicin/cytarabine

    Download QR code; Print/export ... used for the treatment of acute myeloid leukemia. [4 ... cytarabine is indicated for the treatment of newly-diagnosed ...

  6. List of chemotherapeutic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_chemotherapeutic...

    This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer.This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.

  7. Quizartinib - Wikipedia

    en.wikipedia.org/wiki/Quizartinib

    Quizartinib is indicated, in combination with standard cytarabine and anthracycline induction and cytarabine consolidation, and as maintenance monotherapy following consolidation chemotherapy, for the treatment of newly diagnosed acute myeloid leukemia with FLT3 internal tandem duplication (ITD)-positive. [2] [3]

  8. 7+3 (chemotherapy) - Wikipedia

    en.wikipedia.org/wiki/7+3_(chemotherapy)

    "7+3" in the context of chemotherapy is an acronym for a chemotherapy regimen that is most often used today (as of 2014) as first-line induction therapy (to induce remission) in acute myelogenous leukemia, [1] [2] excluding the acute promyelocytic leukemia form, which is better treated with ATRA and/or arsenic trioxide and requires less chemotherapy (if requires it at all, which is not always ...

  9. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Treatment of people aged twelve years of age and older with solid tumors that: have a neurotrophic tyrosine receptor kinase (NTRK) gene fusion, are locally advanced or metastatic or where surgical resection is likely to result in severe morbidity, and have progressed following treatment or have no satisfactory alternative therapy [2]