Search results
Results from the WOW.Com Content Network
It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd 3+), and is used in form of the meglumine salt (gadoterate meglumine). [4] [5] The paramagnetic property of gadoteric acid reduces the T1 relaxation time (and to some extent the T2 and T2* relaxation times) in MRI, which is the source of its clinical utility. Because ...
Free Gd 3+ has a median lethal dose of 0.34 mmol/kg (IV, mouse) [27] or 100–200 mg/kg, but the LD50 is increased by a factor of 31 times [28] when Gd 3+ is chelated. [29] The spectrum of adverse drug reactions is greater with gadolinium-based contrast agents than with iodinated contrast agents (radiocontrast agents). [30]
Gadopentetic acid, sold under the brand name Magnevist, is a gadolinium-based MRI contrast agent. [2]It is usually administered as a salt of a complex of gadolinium with DTPA (diethylenetriaminepentacetate) with the chemical formula A 2 [Gd(DTPA)(H 2 O)]; when cation A is the protonated form of the amino sugar meglumine the salt goes under the name "gadopentetate dimeglumine".
No. of Billionaires: 813 Drivers of Wealth: Technology, finance, entertainment Famous Billionaire: Elon Musk 2. China
In the form of the methylglucamine salt meglumine gadobenate or gadobenate dimeglumine , it is used as a gadolinium-based MRI contrast medium. [4] BOPTA is a derivative of DTPA in which one terminal carboxyl group, –C(O)OH is replaced by -C–O–CH 2 C 6 H 5. Thus gadobenic acid is closely related to gadopentetic acid.
(Reuters) -Los Angeles-based asset management firms overseeing more than $4 trillion in assets are grappling with the impact of the region's destructive wildfires on their operations, with some ...
A new HGTV designer is taking the reins on Love It or List It!. Following longtime co-host Hilary Farr's announcement that she was leaving the show in 2023 after 19 seasons, the long-running HGTV ...
Meglumine is a sugar alcohol derived from glucose that contains an amino group modification. It is often used as an excipient in pharmaceuticals [ 1 ] and in conjunction with iodinated compounds in contrast media such as diatrizoate meglumine , iothalamate meglumine , and iodipamide meglumine .