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  2. Bleeding time - Wikipedia

    en.wikipedia.org/wiki/Bleeding_time

    The time from when the incision is made until all bleeding has stopped is measured and is called the bleeding time. Every 30 seconds, filter paper or a paper towel is used to draw off the blood. The test is finished when bleeding has stopped. [6] A prolonged bleeding time may be a result from decreased number of thrombocytes or impaired blood ...

  3. Factor XIII deficiency - Wikipedia

    en.wikipedia.org/wiki/Factor_XIII_deficiency

    Bleeding tendencies similar to hemophiliacs develop, such as hemarthroses and deep tissue bleeding. As Factor XIII is composed of two subunit protein, A and B, for which the genes are located on different chromosomes, administration of recombinant A subunit improves clot stability and is becoming a therapeutic option for patients with this ...

  4. Factor XII deficiency - Wikipedia

    en.wikipedia.org/wiki/Factor_xii_deficiency

    The condition is diagnosed by blood tests in the laboratory when it is noted that special blood clotting test are abnormal. Specifically Activated Partial Thromboplastin Time (aptt) is prolonged. [2] The diagnosis is confirmed by an assay detecting very low or absent FXII levels. [citation needed] The FXII (F12) gene is found on chromosome 5q33 ...

  5. Mixing study - Wikipedia

    en.wikipedia.org/wiki/Mixing_study

    Fresh normal plasma has all the blood coagulation factors with normal levels. If the problem is a simple factor deficiency, mixing the patient plasma 1:1 with plasma that contains 100% of the normal factor level results in a level ≥50% in the mixture (say the patient has an activity of 0%; the average of 100% + 0% = 50%). [3]

  6. Bleeding diathesis - Wikipedia

    en.wikipedia.org/wiki/Bleeding_diathesis

    In medicine , bleeding diathesis is an unusual susceptibility to bleed mostly due to hypocoagulability (a condition of irregular and slow blood clotting), in turn caused by a coagulopathy (a defect in the system of coagulation).

  7. Haemophilia - Wikipedia

    en.wikipedia.org/wiki/Haemophilia

    Haemophilia (British English), or hemophilia (American English) [6] (from Ancient Greek αἷμα (haîma) 'blood' and φιλία (philía) 'love of'), [7] is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. [2] [3] This results in people bleeding for a longer time after ...

  8. Coagulopathy - Wikipedia

    en.wikipedia.org/wiki/Coagulopathy

    Coagulopathy (also called a bleeding disorder) is a condition in which the blood's ability to coagulate (form clots) is impaired. [1] This condition can cause a tendency toward prolonged or excessive bleeding ( bleeding diathesis ), which may occur spontaneously or following an injury or medical and dental procedures.

  9. Hyperfibrinolysis - Wikipedia

    en.wikipedia.org/wiki/Hyperfibrinolysis

    The affected individuals show a hemophilia-like bleeding phenotype. Acquired hyperfibrinolysis is found in liver disease , [ 3 ] in patients with severe trauma , [ 4 ] during major surgical procedures, [ 5 ] and other conditions. [ 6 ]

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