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Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [23] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction , thus causing flaccid paralysis . [ 24 ]
Newsvendor model. The newsvendor (or newsboy or single-period[ 1] or salvageable) model is a mathematical model in operations management and applied economics used to determine optimal inventory levels. It is (typically) characterized by fixed prices and uncertain demand for a perishable product. If the inventory level is , each unit of demand ...
The elements of the traditional rate formula are defined as: R is the utility's total revenue requirement or rate level. This is the total amount of money a regulator allows a utility to collect from customers. O is the utility's operating expenses, which are passed through to customers at cost with no mark-up. Examples include labor (for ...
Sources say the pharmaceutical company that manufactures Botox, Allergan, charges providers around $6-7 per unit, making the average patient cost more like $10-15 per unit (with metropolitan areas ...
Futures contracts and cost basis. Calculating the cost basis for futures contracts involves assessing the difference between a commodity’s local spot price and its associated futures price. For ...
Average wholesale price. In the United States, the average wholesale price ( AWP) is a prescription drug term referring to the average price for medications offered at the wholesale level. [ 1] The metric was originally intended to convey real pricing information to third-party payers, including government prescription drug programs.
“Preventative Botox involves using Botox injections before wrinkles and fine lines become deeply etched into the skin,” explains New York- and California-based dermatologist Dr. Karyn Grossman ...
The wholesale price index (WPI) is based on the wholesale price of a few relevant commodities of over 240 commodities available. The commodities chosen for the calculation are based on their importance in the region and the point of time the WPI is employed. For example, in India about 435 items were used for calculating the WPI in base year ...