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Voltage-gated ion channels have a crucial role in excitable cells such as neuronal and muscle tissues, allowing a rapid and co-ordinated depolarization in response to triggering voltage change. Found along the axon and at the synapse, voltage-gated ion channels directionally propagate electrical signals. Voltage-gated ion-channels are usually ...
Ion channels are located within the membrane of all excitable cells, [ 3] and of many intracellular organelles. They are often described as narrow, water-filled tunnels that allow only ions of a certain size and/or charge to pass through. This characteristic is called selective permeability.
These ion channels have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. TRP channels were initially discovered in the so-called "transient receptor potential" mutant (trp-mutant) strain of the fruit fly Drosophila, hence their name (see History of Drosophila TRP channels below). Later, TRP channels ...
Ion Television is a television network based in the United States made up of 44 owned-and-operated stations and 194 network affiliates, 164 of which broadcast as digital subchannels. [ 1] The Ion-owned stations are a part of the Ion Media unit of Scripps Networks, a wholly-owned subsidiary of the E. W. Scripps Company.
A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, [ 1] which are a type of calcium channel regulated by changes in membrane potential. Some calcium channels are regulated by the binding of a ligand. [ 2][ 3] Other calcium channels can also be ...
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Voltage-gated sodium channels ( VGSCs ), also known as voltage-dependent sodium channels ( VDSCs ), are a group of voltage-gated ion channels found in the membrane of excitable cells ( e.g., muscle, glial cells, neurons, etc.) with a permeability to the sodium ion Na +. They are the main channels involved in action potential of excitable cells.
Sodium channel. C is the sodium channel. Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na +) through a cell's membrane. [ 1][ 2] They belong to the superfamily of cation channels .