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  2. Thyroglobulin - Wikipedia

    en.wikipedia.org/wiki/Thyroglobulin

    Anti-thyroglobulin antibodies are present in 1 in 10 normal individuals, and a greater percentage of patients with thyroid carcinoma. The presence of these antibodies can result in falsely low (or rarely falsely high) levels of reported thyroglobulin, a problem that can be somewhat circumvented by concomitant testing for the presence of ATAs.

  3. Antithyroid autoantibodies - Wikipedia

    en.wikipedia.org/wiki/Antithyroid_autoantibodies

    Antithyroid autoantibodies (or simply antithyroid antibodies) are autoantibodies targeted against one or more components on the thyroid. The most clinically relevant anti-thyroid autoantibodies are anti- thyroid peroxidase antibodies (anti-TPO antibodies, TPOAb), thyrotropin receptor antibodies (TRAb) and thyroglobulin antibodies (TgAb).

  4. Hashimoto's thyroiditis - Wikipedia

    en.wikipedia.org/wiki/Hashimoto's_thyroiditis

    The two antibodies most commonly implicated in autoimmune thyroiditis are antibodies against thyroid peroxidase (TPOAb) and thyroglobulin (TgAb). They are hypothesized to develop as a result of thyroid damage, where T-lymphocytes are sensitized to residual thyroid peroxidase and thyroglobulin, rather than as the cause of thyroid damage. [47]

  5. Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Graves'_disease

    Graves' disease is an autoimmune disorder, in which the body produces antibodies that are specific to a self-protein - the receptor for thyroid-stimulating hormone. (Antibodies to thyroglobulin and to the thyroid hormones T3 and T4 may also be produced.) These antibodies cause hyperthyroidism because they bind to the TSHr and chronically ...

  6. Hashimoto's encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Hashimoto's_encephalopathy

    Hashimoto's encephalopathy, also known as steroid-responsive encephalopathy associated with autoimmune thyroiditis ( SREAT ), is a neurological condition characterized by encephalopathy, thyroid autoimmunity, and good clinical response to corticosteroids. It is associated with Hashimoto's thyroiditis, and was first described in 1966.

  7. Thyroid peroxidase - Wikipedia

    en.wikipedia.org/wiki/Thyroid_peroxidase

    Thyroid peroxidase, also called thyroperoxidase ( TPO ), thyroid specific peroxidase or iodide peroxidase, is an enzyme expressed mainly in the thyroid where it is secreted into colloid. Thyroid peroxidase oxidizes iodide ions to form iodine atoms for addition onto tyrosine residues on thyroglobulin for the production of thyroxine (T 4) or ...

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