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  2. Edaravone - Wikipedia

    en.wikipedia.org/wiki/Edaravone

    Researchers first developed the free radical scavenger edaravone in late 1980s as a treatment for stroke. The approach, introduced by Koji Abe, now at Okayama University Hospital in Japan, aimed to prevent the swelling of the brain which may occur after a stroke.

  3. Free-radical theory of aging - Wikipedia

    en.wikipedia.org/wiki/Free-radical_theory_of_aging

    The free radical theory of aging states that organisms age because cells accumulate free radical damage over time. [1] A free radical is any atom or molecule that has a single unpaired electron in an outer shell. [2] While a few free radicals such as melanin are not chemically reactive, most biologically relevant free radicals are highly ...

  4. Hyaluronic acid - Wikipedia

    en.wikipedia.org/wiki/Hyaluronic_acid

    The introduction of protein-based cross-links, [59] the introduction of free-radical scavenging molecules such as sorbitol, [60] and minimal stabilisation of the HA chains through chemical agents such as NASHA (non-animal stabilised hyaluronic acid) [61] are all techniques that have been used to preserve its shelf life. [62]

  5. Galvinoxyl - Wikipedia

    en.wikipedia.org/wiki/Galvinoxyl

    Galvinoxyl is a commercially available radical scavenger. [1] It finds use both as a probe for studying radical reactions and as an inhibitor of radical polymerization.It may be synthesized by oxidation of the parent phenol with lead dioxide or potassium hexacyanoferrate(III).

  6. Free Radical Research - Wikipedia

    en.wikipedia.org/wiki/Free_Radical_Research

    Free Radical Research, formerly Free Radical Research Communications, is an academic journal that publishes research papers, hypotheses, and reviews on free radicals, redox signaling, antioxidants, and oxidative damage.

  7. Oxidative stress - Wikipedia

    en.wikipedia.org/wiki/Oxidative_stress

    Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]

  8. Timeline of aging research - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_aging_research

    350 BCE — The Greek philosopher Aristotle, arguably the first philosopher to make a serious attempt to scientifically explain aging, proposes his thesis on aging.He suggests that aging is a process by which human and animal bodies, which are naturally hot and wet, gradually become dry and cold, and theorizes that more moisture delays aging.

  9. Spin trapping - Wikipedia

    en.wikipedia.org/wiki/Spin_trapping

    Spin trapping is an analytical technique employed in chemistry [1] and biology [2] for the detection and identification of short-lived free radicals through the use of electron paramagnetic resonance (EPR) spectroscopy. EPR spectroscopy detects paramagnetic species such as the unpaired electrons of free