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The 1998–1999 Malaysia Nipah virus outbreak occurred from September 1998 to May 1999 in the states of Perak, Negeri Sembilan and Selangor in Malaysia. A total of 265 cases of acute encephalitis with 105 deaths caused by the virus were reported in the three states throughout the outbreak. [ 1 ]
Nipah virus outbreaks have been reported in Malaysia, Singapore, Bangladesh and India. The area is known as the Nipah Belt. The highest mortality due to Nipah virus infection was found in Bangladesh, [citation needed] where outbreaks are typically seen in winter. [24] Nipah virus was first seen in 1998 in
A deadly virus called Nipah carried by bats has already caused human outbreaks across South and South East Asia and has "serious epidemic potential", global health and infectious disease ...
The Nipah virus has been classified by the Centers for Disease Control and Prevention as a Category C agent. [24] Nipah virus is one of several viruses identified by WHO as a potential cause of future epidemics in a new plan developed after the Ebola epidemic for urgent research and development toward new diagnostic tests, vaccines and medicines.
Moderna (MRNA) doses the first participant in the phase I study of its investigational mRNA vaccine, targeting the Nipah virus. It also starts a mid-stage study evaluating its Zika virus vaccine.
In its sixth outbreak in the country since 2001 this year, the virus, known for its 70% mortality rate, has claimed two lives out of the six who were infected in a span of few days in September ...
In May 2018, US$25 million was given to U.S.-based Profectus Biosciences, to make a recombinant protein subunit vaccine against Nipah virus. [5] In February 2019, US$31 million was given to the University of Tokyo, to develop a vaccine by inserting the Nipah-virus G gene ("Malaysia strain"), into a measles vector ("Edmonston B strain"). [5]
Nipah virus (NiV) replication cycle As all mononegaviral genomes, Hendra virus and Nipah virus genomes are non-segmented, single-stranded negative-sense RNA. Both genomes are 18.2 kb in length and contain six genes corresponding to six structural proteins.