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Vitamin C supplements among other dietary supplements at a US drug store. Vitamin C has a definitive role in treating scurvy, which is a disease caused by vitamin C deficiency. Beyond that, a role for vitamin C as prevention or treatment for various diseases is disputed, with reviews often reporting conflicting results.
Insulin resistance can be improved or reversed with lifestyle approaches, such as weight reduction, exercise, and dietary changes. There are multiple ways to measure insulin resistance such as fasting insulin levels or glucose tolerance tests, but these are not often used in clinical practice.
Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation, or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life threatening or lethal." [3]
Insulin resistance desensitizes insulin receptors, preventing insulin from lowering blood sugar levels. [38] The leading cause of hyperglycemia in type 2 diabetes is the failure of insulin to suppress glucose production by glycolysis and gluconeogenesis due to insulin resistance. [39] Insulin normally inhibits glycogenolysis, but fails to do so ...
Vitamin C administration may also acidify the urine and could promote the precipitation of kidney stones or drugs in the urine. [20] Although vitamin C can be well tolerated at doses well above what government organizations recommend, adverse effects can occur at doses above 3 grams per day.
Taking a dose of 3,320 International Units (IU) of vitamin D per day was associated with benefits such as blood pressure, cholesterol, and fasting blood glucose, according to a meta-study.
Type 2 diabetes is due to insufficient insulin production from beta cells in the setting of insulin resistance. [13] Insulin resistance, which is the inability of cells to respond adequately to normal levels of insulin, occurs primarily within the muscles, liver, and fat tissue. [60] In the liver, insulin normally suppresses glucose release.
The exact dose of insulin appropriate for each injection depends on the content of the meal/snack, and the individual person's sensitivity to insulin, and is therefore typically calculated by the individual with diabetes or a family member by hand or assistive device (calculator, chart, mobile app, etc.). [53]