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At higher doses, niacin has been used to treat high cholesterol and triglyceride levels, since it can help lower LDL (“bad”) cholesterol and raise levels of HDL (“good”) cholesterol.
The niacin derivative acipimox is also associated with a modest decrease in LDL. Bile acid sequestrants (resins, e.g. cholestyramine) are particularly effective for lowering LDL-C by sequestering the cholesterol-containing bile acids released into the intestine and preventing their reabsorption from the intestine. It decreases LDL by 15–30% ...
The researcher also said those taking niacin for the cholesterol-lowering effects would find better treatments elsewhere, as previous research has shown niacin to be less effective than other ...
Pharmacologic (1- to 3-gram/day) niacin doses increase HDL levels by 10–30%, [62] making it the most powerful agent to increase HDL-cholesterol. [63] [64] A randomized clinical trial demonstrated that treatment with niacin can significantly reduce atherosclerosis progression and cardiovascular events. [65]
Salmon. This fatty fish is one of nature’s best sources of omega-3s. A 2023 study published in the Journal of the American Heart Association found that consuming 2 grams of EPA and DHA—the two ...
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a lipid-lowering agent.It reduces triglyceride levels and increases HDL cholesterol. It may have less marked adverse effects than niacin, although it is unclear whether the recommended dose is as effective as standard doses of niacin.
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