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Like Lewy bodies, Lewy neurites are a feature of α-synucleinopathies such as dementia with Lewy bodies, Parkinson's disease, and multiple system atrophy. [21] They are also found in the CA2-3 region of the hippocampus in Alzheimer's disease .
Parkinson's disease dementia (PDD) is dementia that is associated with Parkinson's disease (PD). [1] Together with dementia with Lewy bodies (DLB), it is one of the Lewy body dementias characterized by abnormal deposits of Lewy bodies in the brain. [2] [3] [4] [5]
A genetic architecture that predisposes an individual to some disease phenotypes is found in Parkinson's disease and the Lewy body dementias. The presence of Lewy bodies is a link between these disorders; the term 'diseases with Lewy bodies' therefore may be more accurate than 'Lewy body disease'. [16]
Dementia with Lewy bodies (DLB) is a type of dementia, a group of diseases involving progressive neurodegeneration of the central nervous system. [11] It is one of the two Lewy body dementias, along with Parkinson's disease dementia.
Studies have suggested that aggregations of a protein — alpha synuclein — in the brain form Lewy bodies, and lead to the loss of dopaminergic neurons, a key feature of Parkinson’s disease ...
There are two types of Lewy body dementia: dementia with Lewy bodies and Parkinson’s disease dementia. “Lewy body dementia is different from other forms of dementia based on the type of ...
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